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Sexually transmitted infections (STIs) and the diseases they cause (STDs) are considered to be the oldest and most fundamental parts of dermatological care. The modern acronym; STI, was introduced to replace the classic but also stigmatizing notion of sexually transmitted diseases. This was necessary to prevent people from feeling ashamed because of their disease and to include diseases which can spread without sexual contact as well. In addition to the „classic”, well-known venereal diseases, new diseases are also covered by the new term. The significance of these diseases continues to play a prominent role in practice. Screening for sexually transmitted infections, evaluating results, and treating diseases require great expertise.